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Begin Your Journey to Longevity
Av. Gral Ferreira 3170-C Madero Sur 22046 Tijuana, B.C.
MX: +52 (664) 630 5024
US: +1 (619) 860 7551
According to the World Health Organization (WHO), aging is the primary risk factor for the development of chronic-degenerative diseases. Under the paradigm of functional and regenerative medicine, we understand that aging is not simply an inevitable destiny, but a complex biological process that can be analyzed and reverted.
“These hallmarks are interconnected and can reinforce each other over time, leading to a progressive decline in physiological function and an increased risk of age-related diseases.”
The “Hallmarks of Aging” refer to a set of interconnected biological processes that occur at the cellular and molecular levels. These mechanisms are considered the underlying causes of organic deterioration. Currently, scientific literature recognizes 12 fundamental pillars of aging:
The failure of the cellular “recycling” system to clear out
damaged organelles and debris, leading to cellular toxicity
and dysfunction.
The progressive shortening of the protective caps at the
ends of chromosomes, leading to cellular senescence
and cell death.
The failure of the body's mechanisms to maintain the
correct folding and degradation of proteins, leading to
their accumulation.
The decline in the efficiency of cellular powerhouses,
resulting in reduced cellular energy and decreased
ATP production.
The depletion of the body's pool of progenitor and stem
cells, limiting its capacity for regeneration and repair.
A low-grade, persistent inflammatory state that accelerates
the aging process and contributes to degenerative diseases.
Refers to the accumulation of DNA damage over time,
which can lead to mutations and cellular dysfunction.
Changes in gene expression patterns that do not involve
DNA sequence alterations, impacting how cells respond
to their environment and age.
The impairment of metabolic pathways (such as mTOR
and insulin signaling) that regulate how cells respond
to energy availability.
The state in which damaged cells stop dividing but remain metabolically active, secreting pro-inflammatory factors
that damage surrounding tissues.
The disruption of signaling between cells, leading to
systemic inflammation and decreased tissue coordination.
The imbalance of microbial communities in the gut and
other organs, which impacts metabolic health, immunity,
and overall well-being.
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Av. Gral Ferreira 3170-D
Madero Sur
22046 Tijuana, B.C.